New gene-editing method could possibly be used to remove disease-causing mutations from pedigree canine breeds and even from clones of particular person canines



Life



22 July 2022

Two beagle puppies

Gene-edited beagle puppies

Okjae Koo/ToolGen

Two beagle canines have been born in South Korea from cloned pores and skin cells altered by CRISPR gene modifying. CRISPR-edited canines have beforehand been created by altering fertilised eggs, however that is the primary time they’ve been created by cloning.

Many pure-bred pedigree canines have disease-causing mutations. Gene modifying could possibly be used to remove these with out affecting different traits. So, for this objective, the cloning method has benefits over the editing-eggs method, says Okjae Koo at biotech firm ToolGen.”[It] is extra dependable for producing varied pure-bred …

By 24H

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