The COVID pandemic is in no way over. Regardless of plunging case numbers within the U.S. as of this writing, many international locations on the planet are nonetheless experiencing peak an infection charges. And it’s not possible to foresee how the SARSCoV- 2 saga will unfold within the coming months or years. Since 2020 on this nation (and others), laborious truths about our poor health-care system, rampant societal inequality and flawed policy-making engine, to call just a few, have crystallized—painfully in some circumstances.

On the identical time, vaccine expertise, spurred by the profitable deployment of mRNA photographs, has catapulted progress on remedies for a slew of different infectious ailments from malaria to most cancers (as author Mike Could detailed final yr). And medicines for COVID itself are beneath such intense analysis and improvement, that a number of highly effective treatments are at present accessible, with extra within the pipeline (see “These Are the Newest COVID Remedies”). Such developments are solely a part of a brand new arsenal of methods for confronting a future challenged by COVID and some other virus that may come up (see “Getting ready for the Subsequent Plague”). It’s too flip to name this progress a silver lining within the midst of a lot toil and grief. However it’s a vital win.